Cyclic Vomiting Syndrome
Mitochondrial dysfunction is believed to be a factor in the pathogenesis of cyclic vomiting syndrome. Identifying that there is an underlying mitochondrial component to CVS can be very helpful, and allows doctors to consider directed treatment options. Until recently, CVS has been difficult to diagnose because episodes can be infrequent and misdiagnosed.
Fortunately, genetic testing can now identify specific variants responsible for mitochondrial dysfunction. Courtagen Life Sciences offers two Next Generation Sequencing tests to identify variants involved in mitochondrial function.
- The mtSEEK® test provides mitochondrial genome sequencing with deletion detection and heteroplasmy analysis of all 37 genes of the mitochondrial genome.
- The nucSEEK® test is a comprehensive sequence analysis of over 1,100 genes in the nuclear mitochondrial exome. These nuclear DNA gene products are involved in maintaining proper mitochondrial function.